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IGF-1LR3 + GHRP-6 (Blend)
IGF-1 LR3 and GHRP-6 are often combined in research to promote muscle growth and recovery by activating both direct anabolic pathways through IGF-1 and indirect GH-driven mechanisms via ghrelin receptor stimulation.
Quantity: 1
All peptides arrive in powdered form for stability
Third-Party Verified Purity
Each batch is tested and certified to meet or exceed 99% purity standards.
Made in the USA
Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.
Rigorous Quality Control
Double-tested to ensure the highest quality for the most effective research.
What is IGF-1LR3 + GHRP-6 (Blend)?
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic, extended half-life analog of human IGF-1, a hormone that plays a critical role in muscle growth, repair, and cellular regeneration. The LR3 modification extends IGF-1’s active window from minutes to over 20 hours, enhancing its potential biological effects. GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that stimulates the release of growth hormone (GH) by activating ghrelin receptors. In research settings, combining IGF-1 LR3 and GHRP-6 may influence both direct anabolic signaling (via IGF-1) and indirect anabolic effects through increased GH and IGF-1 production.
Potential Benefits Shown in Studies
- Enhanced Muscle Growth & Recovery
- Prolonged Anabolic Signaling Window
- Synergistic GH and IGF‑1 Elevation
- Improved Cellular Repair & Regeneration
- Increased Appetite & Nutrient Intake Support
Mechanisms of Action
IGF-1 LR3 + GHRP-6 may work together by:
- IGF-1 LR3: Binding to IGF-1 receptors in muscle and connective tissue to stimulate protein synthesis and promote cell growth
- GHRP-6: Activating ghrelin receptors (GHS-R1a) to trigger GH release from the pituitary, which in turn increases natural IGF-1 production
- Enhancing satellite cell activation in muscle tissue, supporting repair and hypertrophy
- Promoting collagen production and connective tissue recovery in research models
- Supporting nutrient partitioning, potentially improving muscle-to-fat ratio
- Providing both immediate (LR3) and secondary (GH-mediated) IGF-1 pathways for tissue growth and regeneration
Molecular Structure of Blend Components
IGF-1 LR3 Sequence
MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
Molecular Properties
Note: This version has a substitution of Arg (R) at position 3 and an extended N-terminal peptide chain.
IGF-1LR3 + GHRP-6 (Blend) Research Highlights
IGF‑1 LR3 features an arginine substitution at position 3 and a 13-amino-acid N‑terminal extension, making it approximately three times more potent than native IGF‑1, with a significantly longer circulating half-life of ~20–30 hours.
Source: wikipedia
IGF‑1 LR3 is widely used in lab models for studying cell proliferation, metabolic regulation, stem cell maintenance, and tissue regeneration due to its long-lasting bioactivity.
Source: tydes
GHRP‑6, a synthetic hexapeptide, is known for its high potency in stimulating growth hormone (GH) secretion via the ghrelin receptor, distinguishing it from GHRH-based pathways.
Source: springer
In rat models, GHRP‑6 administered alongside doxorubicin prevented heart failure and multi-organ damage, boosting antioxidant defenses, preserving mitochondrial integrity, and reducing fibrosis.
Source: frontiers
Studies show that central administration of GHRP‑6 in rats triggers feeding behavior, activating hypothalamic and brainstem regions—even when animals had no access to food.
Source: academic