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GHK-Cu (Copper Peptide)

GHK-Cu (Copper Peptide)

GHK-Cu is a naturally occurring copper-binding peptide made of three amino acids (glycine-histidine-lysine) bound to a copper ion. It is widely researched for its powerful effects on skin regeneration, wound healing, and anti-aging. GHK-Cu is naturally found in human plasma but declines with age, which is why it's gaining attention in regenerative and cosmetic science.

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All peptides arrive in powdered form for stability

What is GHK-Cu (Copper Peptide)?

GHK-Cu is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) that binds to copper ions and plays a key role in tissue regeneration, wound healing, skin remodeling, and anti-aging processes. First identified in human plasma, GHK-Cu levels decline with age, but research suggests that restoring it can reverse visible signs of aging and stimulate cellular repair across multiple tissues.

Potential Benefits Shown in Studies

  • Stimulating collagen and elastin production
  • Repairing damaged skin and reducing wrinkles
  • Speeding up wound healing and reducing scar tissue
  • Supporting hair growth and scalp health
  • Reducing inflammation and oxidative stress
  • Regenerating nerves and blood vessels
  • Improving overall skin tone and firmness

Mechanisms of Action

GHK-Cu promotes healing and regeneration by:

  • Activating wound healing genes and tissue remodeling pathways
  • Stimulating collagen and elastin production in skin and joints
  • Promoting angiogenesis (new blood vessel formation)
  • Reducing inflammation and oxidative stress
  • Regulating metalloproteinases for scar-free healing and skin tightening

Because it occurs naturally in the body, GHK-Cu is well tolerated and widely studied in both dermatology and regenerative medicine.

Molecular Structure of GHK-Cu (Copper Peptide)

GHK-Cu (Copper Peptide) molecular structure

Sequence

Gly-His-Lys (with bound Cu²⁺)

Molecular Properties

Formula

C₁₄H₂₄CuN₆O₄

Weight

340.9 g/mol

Source
PubChem

GHK-Cu (Copper Peptide) Research Highlights

Topical application of GHK-Cu has been shown to reduce wrinkles, improve skin elasticity, and enhance firmness by increasing collagen, glycosaminoglycans, and fibroblast activity.

GHK-Cu accelerates wound closure and reduces scar formation by promoting angiogenesis, immune regulation, and tissue matrix rebuilding.

Research supports GHK-Cu's ability to stimulate hair regrowth, likely due to its effects on follicle enlargement, stem cell activation, and improved scalp circulation.

GHK-Cu has been shown to silence pro-inflammatory genes, repair DNA damage, and protect against oxidative stress, making it valuable in both anti-aging and recovery settings.

Disclaimer: GHK-Cu is a research peptide and cosmetic ingredient not FDA-approved for medical use. Information here is for educational purposes only.

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