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Sermorelin + GHRP-2 (Blend)

Sermorelin + GHRP-2 (Blend)

Sermorelin and GHRP-2 are studied together to enhance natural growth hormone release by stimulating both GHRH and ghrelin receptor pathways, potentially amplifying GH output and its regenerative effects.

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All peptides arrive in powdered form for stability

Third-Party Verified Purity
Third-Party Verified Purity

Each batch is tested and certified to meet or exceed 99% purity standards.

Made in the USA
Made in the USA

Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.

Rigorous Quality Control
Rigorous Quality Control

Double-tested to ensure the highest quality for the most effective research.

What is Sermorelin + GHRP-2 (Blend)?

Sermorelin is a synthetic peptide consisting of the first 29 amino acids of naturally occurring growth hormone–releasing hormone (GHRH). It stimulates the pituitary gland to release growth hormone (GH) in a natural, pulsatile pattern. GHRP-2 (Growth Hormone Releasing Peptide-2) is a potent hexapeptide growth hormone secretagogue that activates ghrelin receptors, triggering additional GH release. In research settings, combining Sermorelin and GHRP-2 is explored for its potential to amplify GH output by targeting both the GHRH and ghrelin receptor pathways.

Potential Benefits Shown in Studies

  • Amplified Growth Hormone Release
  • Dual Pathway GH Stimulation (GHRH + Ghrelin Receptor)
  • Improved Recovery & Tissue Repair
  • Support for Lean Muscle Growth
  • Natural, Pulsatile Hormone Secretion

Mechanisms of Action

Sermorelin + GHRP-2 may work together by:

  • Sermorelin: Binding to GHRH receptors to stimulate natural GH pulses that mimic physiological release cycles
  • GHRP-2: Potently activating ghrelin receptors (GHS-R1a) for increased GH pulse amplitude and frequency
  • Increasing circulating IGF-1 to support muscle repair, tissue regeneration, and metabolism
  • Enhancing protein synthesis and collagen formation in research models
  • Supporting recovery, lean muscle preservation, and fat metabolism
  • Combining GHRH and ghrelin pathways for a stronger and more sustained GH elevation

Molecular Structure of Blend Components

Sermorelin molecular structure

Sermorelin Sequence

Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gly

Molecular Properties

Formula

C₁₄₉H₂₄₆N₄₄O₄₂

Weight

~3357.93 g/mol

Source
PubChem
Learn more about Sermorelin

Sermorelin + GHRP-2 (Blend) Research Highlights

Sermorelin, a synthetic analog of GHRH (1–29), stimulates the pituitary gland to secrete growth hormone in natural, pulsatile patterns, maintaining feedback control and minimizing desensitization.

Source: pep-pedia

Originally approved in 1997 for treating childhood growth hormone deficiency, Sermorelin showed efficacy in reversing pediatric growth failure without the constant hormonal exposure of direct GH therapy.

Source: Wikipedia

Studies indicate GHRP-2 produces a stronger GH release than GHRP-6, with a rapid and measurable rise in circulating GH levels.

Source: pubmed

Animal research suggests GHRP-2–induced GH elevation may enhance muscle repair, tendon healing, and collagen synthesis.

Source: pubmed

In animal studies, GHRP‑2 has been shown to suppress pro-inflammatory cytokines like IL‑6 in macrophages and reduce stress hormone release, suggesting systemic immunomodulatory effects.

Source: frontiersin

Its ability to modulate GH release has positioned GHRP‑2 as a research tool for exploring tissue repair, metabolic regulation, cognitive function, bone metabolism, and cardiovascular resilience.

Source: sarasota

Disclaimer: Sermorelin and GHRP-2 are not FDA-approved for combined therapeutic use and are classified as research peptides. This content is intended for educational and informational purposes only.

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