DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. It is illegal to introduce this substance into the body. Only licensed professionals should handle it. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.
Sermorelin
Sermorelin is a synthetic peptide that mimics Growth Hormone-Releasing Hormone (GHRH 1-29)—the natural signal the brain sends to the pituitary gland to release growth hormone (GH). It is primarily studied for its potential to safely and naturally stimulate the body's own GH production, especially in individuals experiencing age-related GH decline.
Quantity: 1
All peptides arrive in powdered form for stability
What is Sermorelin?
Sermorelin is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH 1-29), designed to stimulate the pituitary gland to produce and release endogenous growth hormone (GH). While it has a shorter half-life compared to peptides like CJC-1295, Sermorelin has been widely studied and used for its anti-aging, recovery, and metabolic benefits. It was originally FDA-approved for treating growth hormone deficiency in children.
Potential Benefits Shown in Studies
- Increasing natural growth hormone and IGF-1 levels
- Supporting lean muscle mass and fat loss
- Enhancing recovery, strength, and endurance
- Improving sleep quality and tissue repair
- Promoting youthful skin, hair, and joint health
- Supporting bone density and anti-aging effects
- Boosting energy and overall wellness
Mechanisms of Action
Sermorelin works by:
- Mimicking natural GHRH, binding to pituitary receptors
- Triggering pulsatile GH release, preserving physiologic rhythms
- Increasing IGF-1 levels, promoting muscle repair and cellular regeneration
- Avoiding GH oversaturation, allowing better feedback regulation
- Enhancing fat metabolism and tissue healing via GH/IGF-1 axis
Its action is more natural and self-limiting than exogenous growth hormone, making it ideal for long-term optimization strategies.
Molecular Structure of Sermorelin
Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gly
Molecular Properties
Sermorelin Research Highlights
Sermorelin has been shown to increase GH and IGF-1 levels in both pediatric and adult populations with growth hormone insufficiency.
In clinical use, Sermorelin has been associated with improved lean mass, decreased body fat, and faster post-exercise recovery.
Because GH is naturally released during sleep, Sermorelin may enhance deep sleep cycles, improve recovery, and support tissue repair, especially in older adults.
Unlike direct growth hormone administration, Sermorelin allows the body to regulate how much GH is released, significantly reducing the risk of GH-related side effects.
