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DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. It is illegal to introduce this substance into the body. Only licensed professionals should handle it. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.

CJC-1295 (no DAC) + Ipamorelin (Blend)

CJC-1295 (no DAC) + Ipamorelin (Blend)

CJC-1295 (no DAC) and Ipamorelin are studied together for their potential to enhance natural growth hormone release through dual pathways—mimicking the body’s physiologic rhythm without impacting cortisol or prolactin.

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All peptides arrive in powdered form for stability

Third-Party Verified Purity
Third-Party Verified Purity

Each batch is tested and certified to meet or exceed 99% purity standards.

Made in the USA
Made in the USA

Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.

Rigorous Quality Control
Rigorous Quality Control

Double-tested to ensure the highest quality for the most effective research.

What is CJC-1295 (no DAC) + Ipamorelin (Blend)?

CJC-1295 without Drug Affinity Complex (no DAC) is a synthetic analog of growth hormone–releasing hormone (GHRH) that stimulates the pituitary gland to naturally release growth hormone (GH) in short, physiologic pulses. Unlike the DAC version, the no DAC form has a much shorter half-life, allowing GH release patterns to more closely mimic the body’s natural rhythm. Ipamorelin is a selective growth hormone secretagogue (GHS) and ghrelin receptor agonist that increases GH secretion without significantly affecting cortisol or prolactin. When studied together, these peptides may have complementary effects on GH output and recovery.

Mechanisms of Action

CJC-1295 (no DAC) + Ipamorelin may work together by:

  • CJC-1295 (no DAC): Binding to GHRH receptors to boost GH pulse amplitude and frequency in a short-acting, natural pattern
  • Ipamorelin: Activating ghrelin receptors (GHS-R1a) to enhance GH pulses without unwanted hormone spikes
  • Increasing circulating IGF-1 to support protein synthesis, tissue repair, and metabolic regulation
  • Supporting lean muscle preservation, connective tissue health, and fat metabolism in research models
  • Enhancing overall GH output by combining two distinct hormone stimulation pathways

Molecular Structure of Blend Components

CJC-1295 (No DAC) molecular structure

CJC-1295 (No DAC) Sequence

Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser

Molecular Properties

Formula

C₁₅₂H₂₅₂N₄₄O₄₂

Weight

3367.88 g/mol

Source
PubChem
Learn more about CJC-1295 (No DAC)

CJC-1295 (no DAC) + Ipamorelin (Blend) Research Highlights

CJC‑1295 without DAC is a short-acting analog of GHRH that reproduces the body’s natural growth hormone (GH) pulse patterns, with a half-life of around 30 minutes.

Source: pep-pedia

Its short duration allows for frequent administration that avoids pituitary down-regulation—a key advantage for maintaining physiologic GH sensitivity.

Source: hkroids

Used in conjunction with GHRP peptides like Ipamorelin, CJC‑1295 (no DAC) can enhance GH pulse amplitude and stimulate downstream IGF‑1 signaling for anabolic effects.

Clinical and preclinical studies have linked CJC‑1295 (general notes across versions) to increases in GH/IGF‑1, improvements in body composition, sleep, and anti-aging markers—though human data remains limited for No DAC specifically.

Ipamorelin binds specifically to the ghrelin receptors in the pituitary, inducing growth hormone (GH) release without significantly impacting cortisol, ACTH, or prolactin—offering a cleaner profile compared to other GHRPs.

Source: pep-pedia

Animal studies indicate that Ipamorelin may counteract glucocorticoid-induced muscle catabolism and increase bone mineral content, particularly enhancing tibial growth and bone density in female rats.

Source: sagepub

Ipamorelin closely mimics natural GH secretion patterns by delivering targeted pulses, which helps maintain physiological hormone balance and potentially improves metabolic responses.

Due to its selectivity and minimal hormonal side effects, Ipamorelin is under investigation as a research tool for muscle recovery, anti-aging protocols, and metabolic studies.

Source: regentherapy

Disclaimer: CJC-1295 (no DAC) and Ipamorelin are not FDA-approved for combined therapeutic use and are classified as research peptides. This content is intended for educational and informational purposes only.

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