DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. It is illegal to introduce this substance into the body. Only licensed professionals should handle it. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.
CJC-1295 (No DAC)
CJC-1295 (without DAC) is a synthetic peptide designed to mimic Growth Hormone-Releasing Hormone (GHRH), stimulating the pituitary gland to naturally produce and release growth hormone (GH). Unlike the DAC version, CJC-1295 (No DAC) has a shorter half-life, making it better suited for more controlled and pulsatile GH release—closer to the body's natural rhythm.
Quantity: 1
All peptides arrive in powdered form for stability
What is CJC-1295 (No DAC)?
CJC-1295 (No DAC) is a synthetic peptide that mimics Growth Hormone-Releasing Hormone (GHRH 1-29), designed to stimulate pulsatile release of natural growth hormone (GH). Unlike its DAC-modified counterpart, this version of CJC-1295 has a shorter half-life (~30 minutes), producing more physiologic GH pulses without prolonged systemic elevation. It is often studied for its effects on recovery, muscle repair, fat metabolism, and anti-aging support.
Potential Benefits Shown in Studies
- Boosting natural growth hormone and IGF-1 levels
- Supporting lean muscle growth and recovery
- Reducing body fat through enhanced metabolism
- Improving sleep quality and tissue regeneration
- Promoting anti-aging effects on skin and joints
- Enhancing energy, strength, and endurance
- Supporting cellular repair and immune function
Mechanisms of Action
CJC-1295 (No DAC) operates by:
- Binding to GHRH receptors in the pituitary gland
- Stimulating natural GH release in pulses, mimicking physiologic secretion
- Elevating IGF-1 levels, which mediate many of GH's anabolic effects
- Avoiding desensitization due to its shorter active window
- Reducing fat mass and supporting lean tissue repair
This version is often used in combination with Ipamorelin to amplify GH release while preserving the body's natural rhythms.
Molecular Structure of CJC-1295 (No DAC)
Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser
Molecular Properties
CJC-1295 (No DAC) Research Highlights
CJC-1295 (No DAC) effectively increases endogenous GH and IGF-1 without increasing prolactin or cortisol levels, offering a cleaner safety profile compared to earlier GH secretagogues.
The GH/IGF-1 pathway promoted by CJC-1295 is central to muscle growth, tissue healing, and performance recovery, particularly when combined with resistance training or physical rehabilitation.
Increased GH levels are associated with lipolysis, particularly of visceral fat, making CJC-1295 a target of interest for metabolic and aesthetic research.
Because GH is naturally secreted during deep sleep, stimulating GH release with CJC-1295 may improve sleep quality, REM cycles, and overnight recovery in research models.
