DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. It is illegal to introduce this substance into the body. Only licensed professionals should handle it. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.
Ipamorelin
Ipamorelin is a selective growth hormone secretagogue (GHS) peptide that stimulates the body's natural production of growth hormone (GH). It works by mimicking ghrelin, the "hunger hormone," but without significantly increasing cortisol or other unwanted side effects seen with older GH peptides. It's commonly studied for its potential benefits in muscle growth, recovery, and anti-aging.
Quantity: 1
All peptides arrive in powdered form for stability
What is Ipamorelin?
Ipamorelin is a synthetic growth hormone secretagogue and selective ghrelin receptor agonist. It is part of the GHRP (Growth Hormone Releasing Peptide) family but is distinct in its high selectivity and minimal side effects. Unlike earlier GHRPs such as GHRP-6 or GHRP-2, Ipamorelin does not significantly elevate cortisol or prolactin, making it a cleaner and more targeted option for stimulating endogenous growth hormone release.
Potential Benefits Shown in Studies
- Increasing natural growth hormone levels
- Supporting lean muscle development
- Enhancing recovery from workouts or injuries
- Improving sleep quality and depth
- Reducing body fat and improving metabolism
- Supporting skin elasticity and anti-aging effects
- Promoting bone strength and density
Mechanisms of Action
Ipamorelin works by:
- Stimulating the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary gland
- Triggering the natural release of GH in a pulsatile fashion
- Avoiding unwanted effects on appetite, cortisol, and prolactin levels
- Increasing circulating IGF-1 to promote tissue repair and growth
Molecular Structure of Ipamorelin
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (Aib = 2-aminoisobutyric acid, 2-Nal = 2-naphthylalanine)
Molecular Properties
Ipamorelin Research Highlights
In clinical models, Ipamorelin significantly increased GH and IGF-1 levels without causing elevations in cortisol, unlike earlier peptides such as hexarelin or GHRP-6.
Animal and early-stage human studies show that Ipamorelin supports lean muscle growth, tissue repair, and faster recovery from injuries or resistance training.
Ipamorelin has shown potential benefits for joint healing and bone density improvement, likely due to increased IGF-1 levels and downstream collagen synthesis.
Unlike GHRP-6, Ipamorelin does not increase appetite or affect hunger hormones, making it better tolerated in long-term research protocols.
