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CJC-1295 (No DAC) + Ipamorelin + GHRP-2 (Blend)
CJC-1295 (no DAC), Ipamorelin, and GHRP-2 are often combined to boost natural growth hormone release through multiple pathways while maintaining a physiologic, pulsatile rhythm.
Quantity: 1
All peptides arrive in powdered form for stability
Third-Party Verified Purity
Each batch is tested and certified to meet or exceed 99% purity standards.
Made in the USA
Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.
Rigorous Quality Control
Double-tested to ensure the highest quality for the most effective research.
What is CJC-1295 (No DAC) + Ipamorelin + GHRP-2 (Blend)?
CJC-1295 without Drug Affinity Complex (no DAC) is a synthetic analog of growth hormone–releasing hormone (GHRH) that stimulates the pituitary gland to naturally release growth hormone (GH). Unlike the DAC version, it has a much shorter half-life, producing a more physiologic and pulsatile GH release pattern. Ipamorelin is a selective growth hormone secretagogue (GHS) and ghrelin receptor agonist that increases GH secretion without significantly affecting cortisol or prolactin. GHRP-2 (Growth Hormone Releasing Peptide-2) is a potent hexapeptide GHS that targets the ghrelin receptor and triggers strong GH release. In research settings, combining these three peptides may enhance GH output through multiple complementary pathways.
Potential Benefits Shown in Studies
Possible benefits of CJC‑1295 (no DAC) + Ipamorelin + GHRP‑2 Blend:
- Synergistic GH Release
- Enhanced Muscle Growth & Recovery
- Improved Fat Metabolism
- Better Sleep & Well‑being:
- Minimized Hormonal Side Effects
- Preserved Natural Rhythm
Mechanisms of Action
CJC-1295 (no DAC) + Ipamorelin + GHRP-2 may work together by:
- CJC-1295 (no DAC): Binding to GHRH receptors in the pituitary to initiate short bursts of GH release in a natural pulse pattern
- Ipamorelin: Selectively activating ghrelin receptors to release GH without unwanted hormone spikes
- GHRP-2: Potently activating ghrelin receptors for a stronger GH response compared to GHRP-6
- Increasing circulating IGF-1 to support protein synthesis, collagen formation, and recovery processes
- Combining GHRH and ghrelin receptor activation to amplify both GH pulse frequency and amplitude
- Supporting tissue repair, fat metabolism, and muscle preservation in research models
Molecular Structure of Blend Components
CJC-1295 (No DAC) Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser
Molecular Properties
CJC-1295 (No DAC) + Ipamorelin + GHRP-2 (Blend) Research Highlights
Research and user-oriented reviews highlight improved body composition, fat loss, muscle gain, and recovery through increased GH output.
Source: swolverine
Protocols combining these peptides are commonly used to mimic natural GH rhythms, supporting consistent GH pulsatility.
Source: hkroids community
Ipamorelin specifically avoids triggering cortisol or prolactin, offering cleaner GH stimulation.
Source: wikipedia
CJC‑1295 without DAC is a short-acting analog of GHRH that reproduces the body’s natural growth hormone (GH) pulse patterns, with a half-life of around 30 minutes.
Source: pep-pedia
Its short duration allows for frequent administration that avoids pituitary down-regulation—a key advantage for maintaining physiologic GH sensitivity.
Source: hkroids
Used in conjunction with GHRP peptides like Ipamorelin, CJC‑1295 (no DAC) can enhance GH pulse amplitude and stimulate downstream IGF‑1 signaling for anabolic effects.
Source: thepeptidereport
Clinical and preclinical studies have linked CJC‑1295 (general notes across versions) to increases in GH/IGF‑1, improvements in body composition, sleep, and anti-aging markers—though human data remains limited for No DAC specifically.
Source: peptideinstitute
Ipamorelin binds specifically to the ghrelin receptors in the pituitary, inducing growth hormone (GH) release without significantly impacting cortisol, ACTH, or prolactin—offering a cleaner profile compared to other GHRPs.
Source: pep-pedia
Animal studies indicate that Ipamorelin may counteract glucocorticoid-induced muscle catabolism and increase bone mineral content, particularly enhancing tibial growth and bone density in female rats.
Source: sagepub
Ipamorelin closely mimics natural GH secretion patterns by delivering targeted pulses, which helps maintain physiological hormone balance and potentially improves metabolic responses.
Source: propeptidesource
Due to its selectivity and minimal hormonal side effects, Ipamorelin is under investigation as a research tool for muscle recovery, anti-aging protocols, and metabolic studies.
Source: regentherapy
Studies indicate GHRP-2 produces a stronger GH release than GHRP-6, with a rapid and measurable rise in circulating GH levels.
Source: pubmed
Animal research suggests GHRP-2–induced GH elevation may enhance muscle repair, tendon healing, and collagen synthesis.
Source: pubmed
In animal studies, GHRP‑2 has been shown to suppress pro-inflammatory cytokines like IL‑6 in macrophages and reduce stress hormone release, suggesting systemic immunomodulatory effects.
Source: frontiersin
Its ability to modulate GH release has positioned GHRP‑2 as a research tool for exploring tissue repair, metabolic regulation, cognitive function, bone metabolism, and cardiovascular resilience.
Source: sarasota