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CJC-1295 (No DAC) + Ipamorelin + GHRP-2+ Sermorelin (Blend)
CJC-1295 (no DAC), Sermorelin, Ipamorelin, and GHRP-2 are studied together to maximize growth hormone release by stimulating both GHRH and ghrelin pathways through complementary mechanisms.
Quantity: 1
All peptides arrive in powdered form for stability
Third-Party Verified Purity
Each batch is tested and certified to meet or exceed 99% purity standards.
Made in the USA
Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.
Rigorous Quality Control
Double-tested to ensure the highest quality for the most effective research.
What is CJC-1295 (No DAC) + Ipamorelin + GHRP-2+ Sermorelin (Blend)?
CJC-1295 without Drug Affinity Complex (no DAC) is a short-acting analog of growth hormone–releasing hormone (GHRH) that promotes natural GH release in a physiologic pulse pattern. Sermorelin is another synthetic GHRH analog with a shorter amino acid chain (29 amino acids) that also stimulates the pituitary to release GH. Ipamorelin is a selective growth hormone secretagogue (GHS) that activates ghrelin receptors to enhance GH secretion without significantly affecting cortisol or prolactin. GHRP-2 is a potent hexapeptide GHS that targets the same ghrelin receptor but with stronger GH-releasing potency than GHRP-6. In research settings, this combination is explored for potentially maximizing GH output by activating multiple hormonal pathways.
Potential Benefits Shown in Studies
Possible benefits of CJC‑1295 (no DAC) + Sermorelin + Ipamorelin + GHRP‑2 Blend:
- Maximized GH Release
- Improved Muscle Growth & Recovery
- Optimized Fat Metabolism & Body Composition
- Keeps Natural Hormone Rhythm
- Clean Hormonal Profile
- Safe, Feedback-Regulated Action
Mechanisms of Action
CJC-1295 (no DAC) + Ipamorelin + Sermorelin + GHRP-2 may work together by:
- CJC-1295 (no DAC): Binding to GHRH receptors for short bursts of GH release that mimic natural secretion cycles
- Sermorelin: Stimulating GHRH receptors with a shorter-acting profile, potentially increasing pulse frequency
- Ipamorelin: Selectively activating ghrelin receptors for clean GH release without unwanted hormone spikes
- GHRP-2: Strongly activating ghrelin receptors for higher GH pulse amplitude compared to other GHRPs
- Increasing circulating IGF-1 to support protein synthesis, tissue repair, collagen production, and metabolism
- Enhancing recovery, connective tissue health, and fat metabolism in research models
Molecular Structure of Blend Components
CJC-1295 (No DAC) Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser
Molecular Properties
CJC-1295 (No DAC) + Ipamorelin + GHRP-2+ Sermorelin (Blend) Research Highlights
Research and supplier summaries note that using CJC‑1295, Ipamorelin, and GHRP‑2 together enhances GH output more than any single peptide alone.
Source: heall
Combining CJC‑1295 (no DAC) with Ipamorelin has been shown to raise both the amplitude and frequency of growth hormone release—supporting dynamic pulsatility while preserving feedback control.
Source: peptideres
Studies and comparative reviews report this peptide stack supports lean muscle and metabolic enhancement by optimizing GH target engagement.
Source: tydes
CJC‑1295 without DAC is a short-acting analog of GHRH that reproduces the body’s natural growth hormone (GH) pulse patterns, with a half-life of around 30 minutes.
Source: pep-pedia
Its short duration allows for frequent administration that avoids pituitary down-regulation—a key advantage for maintaining physiologic GH sensitivity.
Source: hkroids
Used in conjunction with GHRP peptides like Ipamorelin, CJC‑1295 (no DAC) can enhance GH pulse amplitude and stimulate downstream IGF‑1 signaling for anabolic effects.
Source: thepeptidereport
Clinical and preclinical studies have linked CJC‑1295 (general notes across versions) to increases in GH/IGF‑1, improvements in body composition, sleep, and anti-aging markers—though human data remains limited for No DAC specifically.
Source: peptideinstitute
Ipamorelin binds specifically to the ghrelin receptors in the pituitary, inducing growth hormone (GH) release without significantly impacting cortisol, ACTH, or prolactin—offering a cleaner profile compared to other GHRPs.
Source: pep-pedia
Animal studies indicate that Ipamorelin may counteract glucocorticoid-induced muscle catabolism and increase bone mineral content, particularly enhancing tibial growth and bone density in female rats.
Source: sagepub
Ipamorelin closely mimics natural GH secretion patterns by delivering targeted pulses, which helps maintain physiological hormone balance and potentially improves metabolic responses.
Source: propeptidesource
Due to its selectivity and minimal hormonal side effects, Ipamorelin is under investigation as a research tool for muscle recovery, anti-aging protocols, and metabolic studies.
Source: regentherapy
Sermorelin, a synthetic analog of GHRH (1–29), stimulates the pituitary gland to secrete growth hormone in natural, pulsatile patterns, maintaining feedback control and minimizing desensitization.
Source: pep-pedia
Originally approved in 1997 for treating childhood growth hormone deficiency, Sermorelin showed efficacy in reversing pediatric growth failure without the constant hormonal exposure of direct GH therapy.
Source: Wikipedia
Studies indicate GHRP-2 produces a stronger GH release than GHRP-6, with a rapid and measurable rise in circulating GH levels.
Source: pubmed
Animal research suggests GHRP-2–induced GH elevation may enhance muscle repair, tendon healing, and collagen synthesis.
Source: pubmed
In animal studies, GHRP‑2 has been shown to suppress pro-inflammatory cytokines like IL‑6 in macrophages and reduce stress hormone release, suggesting systemic immunomodulatory effects.
Source: frontiersin
Its ability to modulate GH release has positioned GHRP‑2 as a research tool for exploring tissue repair, metabolic regulation, cognitive function, bone metabolism, and cardiovascular resilience.
Source: sarasota